CXCR3 antibody (AA 1-326)

Catalog No. ABIN7869194

This Rabbit Polyclonal antibody specifically detects CXCR3 in WB, ELISA and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for CXCR3 antibody (AA 1-326) (ABIN7869194)

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CXCR3 Antibody

Binding Specificity: AA 1-326

Purpose: Cxcr3 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids M1-E326) was used as the immunogen for the Cxcr3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cxcr3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cxcr3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: Cxcr3

Background: Chemokine receptor CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. It is mapped to Xq13.1. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in patients with CLL, and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes. It is found that in the absence of known etiologic agents, CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes. CXCR3 signaling is associated with MG pathogenesis and proposed that and CXCR3 may serve as novel drug targets to treat MG. CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1.

UniProt: O88410