FOSB antibody (AA 1-332)

Catalog No. ABIN7869200

This Rabbit Polyclonal antibody specifically detects FOSB in ELISA, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FOSB antibody (AA 1-332) (ABIN7869200)

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSB antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOSB Antibody

Binding Specificity: AA 1-332

Purpose: FosB Antibody

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids M1-S332) was used as the immunogen for the FosB antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FosB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FosB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Alternative Name: FosB

Background: FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

UniProt: P53539