CX3CR1 antibody (AA 1-345)

Catalog No. ABIN7869225

The Rabbit Polyclonal anti-CX3CR1 antibody is suitable to detect CX3CR1 in samples from Human. It has been validated for FACS, ELISA and IHC (p).

Quick Overview for CX3CR1 antibody (AA 1-345) (ABIN7869225)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CX3CR1 Antibody

Binding Specificity: AA 1-345

Purpose: CMKBRL1 Antibody / CX3CR1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-H345) was used as the immunogen for the CMKBRL1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CMKBRL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CMKBRL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CMKBRL1

Background: CX3C chemokine receptor 1 (CX3CR1) also known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13) and Beta chemokine receptor-like 1 (CMKBRL1) is a protein that in humans is encoded by the CX3CR1 gene. Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin