PAN2 antibody (AA 1-356)

Catalog No. ABIN7869245

This Rabbit Polyclonal antibody specifically detects PAN2 in ELISA, WB and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PAN2 antibody (AA 1-356) (ABIN7869245)

Target: PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAN2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-PAN2 Antibody

Binding Specificity: AA 1-356

Purpose: PAN2 Antibody / USP52

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-L356) was used as the immunogen for the PAN2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PAN2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PAN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PAN2

Target: PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))

Alternative Name: PAN2

Background: PAB-dependent poly(A)-specific ribonuclease subunit 2, also called Inactive ubiquitin carboxyl-terminal hydrolase 52 (USP52), is an enzyme that in humans is encoded by the PAN2 gene. This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.

UniProt: Q504Q3