IDO2 antibody (AA 1-357)

Catalog No. ABIN7869246

The Rabbit Polyclonal anti-IDO2 antibody is suitable to detect IDO2 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB, ELISA, FACS and IHC (p).

Quick Overview for IDO2 antibody (AA 1-357) (ABIN7869246)

Target: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IDO2 Antibody

Binding Specificity: AA 1-357

Purpose: Indoleamine 2,3-dioxygenase 2 Antibody / IDO2 / INDOL1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-R357) was used as the immunogen for the Indoleamine 2,3-dioxygenase 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Indoleamine 2,3-dioxygenase 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Indoleamine 2,3-dioxygenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IDO2

Target: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Alternative Name: Indoleamine 2,3-dioxygenase 2

Background: IDO2 (Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.

UniProt: Q6ZQW0