CXCR5 antibody (AA 1-374)

Catalog No. ABIN7869264

The Rabbit Polyclonal anti-CXCR5 antibody is suitable to detect CXCR5 in samples from Mouse and Rat. It has been validated for ELISA and IHC (p).

Quick Overview for CXCR5 antibody (AA 1-374) (ABIN7869264)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CXCR5 Antibody

Binding Specificity: AA 1-374

Purpose: Blr1 Antibody / Cxcr5 / Mdr15

Purification: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids M1-F374) was used as the immunogen for the Blr1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Blr1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Blr1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: Blr1

Background: CXCR5 (Chemokine CXC Motif Receptor 5), also known as BLR1 (Burkitt lymphoma receptor 1) and MDR15 (Monocyte derived receptor 15), is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemo-attractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma (PIOL).

UniProt: Q04683