PCDHB14 antibody (AA 1-374)

Catalog No. ABIN7869265

The Rabbit Polyclonal anti-PCDHB14 antibody (ABIN7869265) specifically detects PCDHB14 in WB, FACS, ELISA and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PCDHB14 antibody (AA 1-374) (ABIN7869265)

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB14 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PCDHB14 Antibody

Binding Specificity: AA 1-374

Purpose: PCDHB14 Antibody

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids M1-D374) was used as the immunogen for the PCDHB14 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PCDHB14 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PCDHB14 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PCDHB14

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Alternative Name: PCDHB14

Background: Protocadherin beta-14 is a protein that in humans is encoded by the PCDHB14 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

UniProt: Q9Y5E9