RAD9A antibody (AA 1-389)
Quick Overview for RAD9A antibody (AA 1-389) (ABIN7869286)
Target
See all RAD9A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-389
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Purpose
- Rad9a Antibody
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Purification
- Affinity purified
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Immunogen
- Recombinant mouse protein (amino acids M1-G389) was used as the immunogen for the Rad9a antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the Rad9a antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the Rad9a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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Alternative Name
- Rad9a
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Background
- This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9Z0F6
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
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