ATG4B antibody (AA 1-392)

Catalog No. ABIN7869289

The Rabbit Polyclonal anti-ATG4B antibody (ABIN7869289) specifically detects ATG4B in WB, ELISA and FACS. The antibody is reactive with Human and Rat samples.

Quick Overview for ATG4B antibody (AA 1-392) (ABIN7869289)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ATG4B Antibody

Binding Specificity: AA 1-392

Purpose: ATG4B Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-L392) was used as the immunogen for the ATG4B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ATG4B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ATG4B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Alternative Name: ATG4B

Background: Cysteine protease ATG4B is an enzyme that in humans is encoded by the ATG4B gene. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: Q9Y4P1

Pathways: Autophagy