FLI1 antibody (AA 1-426)

Catalog No. ABIN7869348

The Rabbit Polyclonal anti-FLI1 antibody is suitable to detect FLI1 in samples from Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for FLI1 antibody (AA 1-426) (ABIN7869348)

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FLI1 Antibody

Binding Specificity: AA 1-426

Purpose: Zebrafish Fli1 Antibody / Friend leukemia integration 1 transcription factor

Purification: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Fli1 recombinant protein (amino acids M1-H426) was used as the immunogen for the Zebrafish Fli1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Fli1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Fli1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FLI1

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Alternative Name: Fli1

Background: Friend leukemia integration 1 transcription factor (FLI1),also known as transcription factor ERGB,is a protein that in humans is encoded by the FLI1 gene,which is a proto-oncogene. It is mapped to 11q24.3. This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11,22)(q24,q12) translocation with the Ewing sarcoma gene on chromosome 22,which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4,11)(q21,q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.