CDR2 antibody (AA 1-441)

Catalog No. ABIN7869367

The Rabbit Polyclonal anti-CDR2 antibody (ABIN7869367) specifically detects CDR2 in ELISA, WB, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for CDR2 antibody (AA 1-441) (ABIN7869367)

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDR2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-CDR2 Antibody

Binding Specificity: AA 1-441

Purpose: CDR2 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-D441) was used as the immunogen for the CDR2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CDR2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CDR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CDR2

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Alternative Name: CDR2

Background: Cerebellar degeneration-related protein 2 is a protein that in humans is encoded by the CDR2 gene. By a combination of study of rodent/human somatic cell hybrids and in situ hybridization, this gene is assigned to 16p13.1-p12. The onconeuronal cerebellar degeneration-related antigen Cdr2 is associated with paraneoplastic syndromes. Neoplastic expression of Cdr2 in ovary and breast tumors triggers an autoimmune response that suppresses tumor growth by developing tumor immunity, but culminates in cerebellar degeneration when Cdr2-specific immune cells recognize neuronal Cdr2.

UniProt: Q01850