LCP1 antibody (AA 1-444)

Catalog No. ABIN7869368

This Rabbit Polyclonal antibody specifically detects LCP1 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LCP1 antibody (AA 1-444) (ABIN7869368)

Target: LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LCP1 Antibody

Binding Specificity: AA 1-444

Purpose: L Plastin Antibody / LCP1

Purification: Antigen affinity purified

Immunogen: Amino acids M1-K444 from the human protein were used as the immunogen for the L Plastin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the L Plastin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the L Plastin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LCP1

Target: LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))

Alternative Name: L Plastin

Background: Plastin-2 is a protein that in humans is encoded by the LCP1 gene. This gene is mapped to 13q14.13. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

UniProt: P13796