RUFY3 antibody (AA 1-469)

Catalog No. ABIN7869388

The Rabbit Polyclonal anti-RUFY3 antibody (ABIN7869388) specifically detects RUFY3 in WB, ELISA and FACS. The antibody is reactive with Mouse, Human and Rat samples.

Quick Overview for RUFY3 antibody (AA 1-469) (ABIN7869388)

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUFY3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RUFY3 Antibody

Binding Specificity: AA 1-469

Purpose: RUFY3 Antibody / RIPx

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-H469) was used as the immunogen for the RUFY3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RUFY3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RUFY3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RUFY3

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Alternative Name: RUFY3

Background: The RUFY3 gene, also called RUN and FYVE domain-containing protein 3 and Rap2-interacting protein x (RIPx), encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.

UniProt: Q7L099