RORB antibody (AA 1-470)

Catalog No. ABIN7869390

The Rabbit Polyclonal anti-RORB antibody is suitable to detect RORB in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for RORB antibody (AA 1-470) (ABIN7869390)

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RORB Antibody

Binding Specificity: AA 1-470

Purpose: ROR beta Antibody / RORB

Purification: Antigen affinity purified

Immunogen: Recombinant human ROR beta/RORB protein (amino acids M1-K470) was used as the immunogen for the ROR beta antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ROR beta antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ROR beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RORB

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Alternative Name: ROR beta

Background: RAR-related orphan receptor beta (ROR-beta), also known as NR1F2 (nuclear receptor subfamily 1, group F, member 2) is a nuclear receptor that in humans is encoded by the RORB gene. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm.

UniProt: Q92753

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway