ME1 antibody (AA 1-572)

Catalog No. ABIN7869482

This Mouse Monoclonal antibody specifically detects ME1 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ME1 antibody (AA 1-572) (ABIN7869482)

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ME1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5E5F7

Product Details anti-ME1 Antibody

Binding Specificity: AA 1-572

Purpose: Malic enzyme 1 Antibody / ME1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-Q572) was used as the immunogen for the Malic enzyme 1 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Malic enzyme 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Malic enzyme 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ME1

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Alternative Name: Malic enzyme 1

Background: NADP-dependent malic enzyme (Malic enzyme 1) is a protein that in humans is encoded by the ME1 gene. This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

UniProt: P48163

Pathways: Regulation of Lipid Metabolism by PPARalpha