PGC antibody (AA 1-622)

Catalog No. ABIN7869503

This Rabbit Polyclonal antibody specifically detects PGC in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for PGC antibody (AA 1-622) (ABIN7869503)

Target: PGC (Pepsinogen C (PGC))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-PGC Antibody

Binding Specificity: AA 1-622

Purpose: PEPC Antibody / PCK1

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-M622) was used as the immunogen for the PEPC antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PEPC antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PEPC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PGC

Target: PGC (Pepsinogen C (PGC))

Alternative Name: PEPC

Background: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

UniProt: P35558