FERMT2 antibody (AA 1-650)

Catalog No. ABIN7869517

The Rabbit Polyclonal anti-FERMT2 antibody (ABIN7869517) specifically detects FERMT2 in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for FERMT2 antibody (AA 1-650) (ABIN7869517)

Target: FERMT2 (Fermitin Family Member 2 (FERMT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FERMT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-FERMT2 Antibody

Binding Specificity: AA 1-650

Purpose: FERMT2 Antibody / Kindlin 2 / KIND2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-I650) was used as the immunogen for the FERMT2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FERMT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FERMT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FERMT2

Target: FERMT2 (Fermitin Family Member 2 (FERMT2))

Alternative Name: FERMT2

Background: Fermitin family homolog 2 (FERMT2), also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or Kindlin-2, is a protein that in humans is encoded by the FERMT2 gene. Enables several functions, including actin binding activity, phosphatidylinositol-3,4,5-trisphosphate binding activity, and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway, positive regulation of cell differentiation, and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol, focal adhesion, and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia.

UniProt: Q96AC1

Pathways: Cell-Cell Junction Organization