The Rabbit Polyclonal anti-KIFC1 antibody (ABIN7869523) specifically detects KIFC1 in WB, IF, ELISA, IHC (p) and FACS.
The antibody is reactive with Human, Mouse and Rat samples.
KIFC1
Reactivity: Human
IF, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the KIFC1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the KIFC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
KIFC1
(Kinesin Family Member C1 (KIFC1))
Alternative Name
KIFC1
Background
Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene. Kinesin superfamily proteins (KIFs) are molecular motors that drive directional, microtubule-dependent intracellular transport of membrane-bound organelles and other macromolecules (e.g. proteins, nucleic acids). The intracellular transport functions of KIFs are fundamentally important for a variety of cellular functions, including mitotic and meiotic division, motility/migration, hormone and neurotransmitter release, and differentiation. Disruptions to KIF-mediated intracellular transport have been linked with a variety of pathologies, ranging from tumorigenesis to defects in higher order brain function such as learning and memory. KIFC1/HSET is a minus-end directed KIF involved in the processing and movement of early endocytic vesicles, as well as microtubule crosslinking and spindle assembly.