S100A5 antibody (AA 1-92)

Catalog No. ABIN7869615

The Mouse Monoclonal anti-S100A5 antibody is suitable to detect S100A5 in samples from Human. It has been validated for IHC (p).

Quick Overview for S100A5 antibody (AA 1-92) (ABIN7869615)

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: S100A5-7475

Product Details anti-S100A5 Antibody

Binding Specificity: AA 1-92

Purpose: S100 calcium binding protein A5 Antibody / S100A5

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-92) from the human protein was used as the immunogen for the S100 calcium binding protein A5 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the S100 calcium binding protein A5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the S100 calcium binding protein A5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for S100A5

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Alternative Name: S100 calcium binding protein A5

Background: The S-100 proteins are small calcium-binding proteins which display different expression patterns in human tissues. Some S-100 proteins are associated with tumor development and the metastatic behavior of tumors. S-100A5 (S100 calcium binding protein A5) is a 92 amino acid protein that belongs to the S-100 family. Containing two EF-hand domains, S-100A5 binds calcium, zinc and copper. One subunit can simultaneously bind two calcium ions or two copper ions plus one zinc ion. Calcium and copper ions compete for the same binding sites on the S-100A5 protein. The S-100A5 protein is expressed in very restricted regions of the adult brain. The S-100A5 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 1q21.3. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Due to the clustered organization of the S-100 proteins a new logical nomenclature based on their physical arrangement on the chromosome has been described, with S-100A1 being closest to the telomere and S-100A9 being closest to the centromere.

UniProt: P33763

Pathways: S100 Proteins