Recombinant CSTA antibody (AA 1-98)

Catalog No. ABIN7869663

The Mouse Monoclonal anti-CSTA antibody is suitable to detect CSTA in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CSTA antibody (AA 1-98) (ABIN7869663)

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CSTA-9087R

Product Details anti-CSTA Antibody

Binding Specificity: AA 1-98

Purpose: Recombinant Cystatin A Antibody / CSTA

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human CSTA protein (within amino acids 1-98) was used as the immunogen for the recombinant Cystatin A antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Cystatin A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant Cystatin A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CSTA

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Alternative Name: Cystatin A

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

UniProt: P01040

Pathways: Response to Water Deprivation