Recombinant CSTA antibody (AA 1-98)

Catalog No. ABIN7869665

This Mouse Monoclonal antibody specifically detects CSTA in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant CSTA antibody (AA 1-98) (ABIN7869665)

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RCSTA-8995

Product Details anti-CSTA Antibody

Binding Specificity: AA 1-98

Purpose: CSTA Antibody / Cystatin A

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human protein (around aa 1-98) was used as the immunogen for the CSTA antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the CSTA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CSTA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CSTA

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Alternative Name: CSTA

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

UniProt: P01040

Pathways: Response to Water Deprivation