MT-ND3 antibody (AA 10-38)

Catalog No. ABIN7869699

The Rabbit Polyclonal anti-MT-ND3 antibody is suitable to detect MT-ND3 in samples from Human. It has been validated for WB and FACS.

Quick Overview for MT-ND3 antibody (AA 10-38) (ABIN7869699)

Target: MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ND3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-MT-ND3 Antibody

Binding Specificity: AA 10-38

Purpose: MT-ND3 Antibody / NADH-ubiquinone oxidoreductase chain 3

Purification: Antigen affinity

Immunogen: A portion of amino acids 10-38 from the human protein was used as the immunogen for this MT-ND3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the MT-ND3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the MT-ND3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MT-ND3

Target: MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))

Alternative Name: MT-ND3

Background: MT-ND3 is a critical subunit of complex I, acting as a catalyst in the transfer of electrons from NADH to ubiquinone. This process is essential for generating the proton gradient necessary for ATP production. Without MT-ND3, the electron transport chain would not be able to function properly, leading to a decrease in ATP production and ultimately, cellular dysfunction. Research has shown that mutations in the gene encoding MT-ND3 can lead to mitochondrial diseases and a range of health problems, including muscle weakness, neurological disorders, and even premature aging.

UniProt: P03897