BCL11B antibody (AA 10-628)

Catalog No. ABIN7869714

The Rabbit Polyclonal anti-BCL11B antibody is suitable to detect BCL11B in samples from Human and Rat. It has been validated for WB, ELISA, IF, FACS and IHC (p).

Quick Overview for BCL11B antibody (AA 10-628) (ABIN7869714)

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BCL11B Antibody

Binding Specificity: AA 10-628

Purpose: B-cell lymphoma/leukemia 11B Antibody / BCL11B

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q10-A628) was used as the immunogen for the B-cell lymphoma/leukemia 11B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the B-cell lymphoma/leukemia 11B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the B-cell lymphoma/leukemia 11B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for BCL11B

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Alternative Name: B-cell lymphoma/leukemia 11B

Background: B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene. This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

UniProt: Q9C0K0