Phospholipase C delta 3 antibody (AA 10-702)

Catalog No. ABIN7869717

The Rabbit Polyclonal anti-Phospholipase C delta 3 antibody is suitable to detect Phospholipase C delta 3 in samples from Human. It has been validated for WB, ELISA, FACS and IF.

Quick Overview for Phospholipase C delta 3 antibody (AA 10-702) (ABIN7869717)

Target: Phospholipase C delta 3 (PLCd3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C delta 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-Phospholipase C delta 3 Antibody

Binding Specificity: AA 10-702

Purpose: PLC-delta-3 Antibody / PLCD3

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R10-Q702) was used as the immunogen for the PLC-delta-3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PLC-delta-3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PLC-delta-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Phospholipase C delta 3

Target: Phospholipase C delta 3 (PLCd3)

Alternative Name: PLC-delta-3

Background: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 is an enzyme that in humans is encoded by the PLCD3 gene. This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.

UniProt: Q8N3E9

Pathways: WNT Signaling