HBa2 antibody (AA 100-128)

Catalog No. ABIN7869722

This Rabbit Polyclonal antibody specifically detects HBa2 in WB and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for HBa2 antibody (AA 100-128) (ABIN7869722)

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBa2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-HBa2 Antibody

Binding Specificity: AA 100-128

Purpose: HBA2 Antibody / Hemoglobin subunit alpha 2

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 100-128 from the human protein was used as the immunogen for the HBA2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the HBA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HBA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HBa2

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Alternative Name: HBA2

Background: HBA2 is a key component of hemoglobin, the protein responsible for transporting oxygen from the lungs to the rest of the body. Together with HBA1, this protein forms a tetramer that binds to oxygen molecules and carries them through the bloodstream. While HBA1 is typically more abundant in adults, HBA2 is essential during fetal development and plays a vital role in ensuring the proper oxygenation of tissues in the growing fetus. Research has shown that mutations in the HBA2 gene can lead to various blood disorders, such as alpha-thalassemia, a condition characterized by reduced production of alpha-globin chains.

UniProt: P69905