MUC13 antibody (AA 100-300)

Catalog No. ABIN7869849

The Mouse Monoclonal anti-MUC13 antibody is suitable to detect MUC13 in samples from Human. It has been validated for IHC (p).

Quick Overview for MUC13 antibody (AA 100-300) (ABIN7869849)

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MUC13-13111

Product Details anti-MUC13 Antibody

Binding Specificity: AA 100-300

Purpose: MUC13 Antibody / Mucin 13

Purification: Protein G affinity

Immunogen: A portion of amino acids 100-300 from human Mucin 13 protein was used as the immunogen for the MUC13 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the MUC13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MUC13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MUC13

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Alternative Name: MUC13

Background: Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.

UniProt: Q9H3R2