Recombinant Uroplakin 3B antibody (AA 100-300)

Catalog No. ABIN7869864

The Rabbit Monoclonal anti-Uroplakin 3B antibody is suitable to detect Uroplakin 3B in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for Recombinant Uroplakin 3B antibody (AA 100-300) (ABIN7869864)

Target: Uroplakin 3B (UPK3B)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Uroplakin 3B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: UPK3B-8768R

Product Details anti-Uroplakin 3B Antibody

Binding Specificity: AA 100-300

Purpose: Uroplakin 3B Antibody / UPK3B (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen for the Uroplakin 3B antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Uroplakin 3B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Uroplakin 3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Uroplakin 3B

Target: Uroplakin 3B (UPK3B)

Alternative Name: Uroplakin 3B

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

UniProt: Q9BT76