Uroplakin 3B antibody (AA 100-300)

Catalog No. ABIN7869866

This Mouse Monoclonal antibody specifically detects Uroplakin 3B in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Uroplakin 3B antibody (AA 100-300) (ABIN7869866)

Target: Uroplakin 3B (UPK3B)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Uroplakin 3B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: UPK3B-3270

Product Details anti-Uroplakin 3B Antibody

Binding Specificity: AA 100-300

Purpose: UPK3B Antibody / Uroplakin 3B (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen for the UPK3B antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the UPK3B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the UPK3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Uroplakin 3B

Target: Uroplakin 3B (UPK3B)

Alternative Name: UPK3B

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

UniProt: Q9BT76