SEC31A antibody (AA 101-806)

Catalog No. ABIN7869901

The Rabbit Polyclonal anti-SEC31A antibody (ABIN7869901) specifically detects SEC31A in ELISA, WB, IF, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SEC31A antibody (AA 101-806) (ABIN7869901)

Target: SEC31A (SEC31 Homolog A (SEC31A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC31A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-SEC31A Antibody

Binding Specificity: AA 101-806

Purpose: SEC31A Antibody

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Y101-K806) was used as the immunogen for the SEC31A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SEC31A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SEC31A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SEC31A

Target: SEC31A (SEC31 Homolog A (SEC31A))

Alternative Name: SEC31A

Background: Protein transport protein Sec31A is a protein that in humans is encoded by the SEC31A gene. The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: O94979

Pathways: ER-Nucleus Signaling