Cx40/GJA5 antibody (AA 102-134)

Catalog No. ABIN7869906

The Rabbit Polyclonal anti-Cx40/GJA5 antibody is suitable to detect Cx40/GJA5 in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for Cx40/GJA5 antibody (AA 102-134) (ABIN7869906)

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cx40/GJA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cx40/GJA5 Antibody

Binding Specificity: AA 102-134

Purpose: Cx40 Antibody / Connexin 40 / GJA5

Immunogen: A portion of amino acids 102-134 from the human protein was used as the immunogen for this Cx40 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Cx40 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Cx40 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cx40/GJA5

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Alternative Name: Cx40

Background: Connexin 40 protein, also known as Cx40, GJA5 and Gap junction alpha-5 protein, plays a role in cell communication and proper function within the body. In the brain, Connexin 40 helps facilitate communication between neurons, allowing for proper cognitive function and coordination. Research suggests that disruptions in Connexin 40 expression may contribute to neurological disorders such as epilepsy and Alzheimer's disease. In the immune system Gap junctions formed by Connexin 40 facilitate the transfer of signaling molecules between immune cells, enabling a coordinated response to pathogens and foreign invaders.

UniProt: P36382

Pathways: Cell-Cell Junction Organization