Lamin B Receptor antibody (AA 102-209)
Quick Overview for Lamin B Receptor antibody (AA 102-209) (ABIN7869911)
Target
See all Lamin B Receptor (LBR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 102-209
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Purpose
- LBR Antibody / Lamin B Receptor
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Purification
- Affinity purified
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Immunogen
- Amino acids H102-F209 from the human protein were used as the immunogen for the LBR antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the LBR antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- -20 °C
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Storage Comment
- Store the LBR antibody at -20oC.
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- Lamin B Receptor (LBR)
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Alternative Name
- LBR
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Background
- Lamin-B receptor is a protein, and in humans, it is encoded by the LBR gene. It is mapped to 1q42.12. The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
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UniProt
- Q14739
Target
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