Filamin A antibody (AA 1025-1054)

Catalog No. ABIN7869924

The Rabbit Polyclonal anti-Filamin A antibody is suitable to detect Filamin A in samples from Human. It has been validated for WB, IF, IHC (p) and FACS.

Quick Overview for Filamin A antibody (AA 1025-1054) (ABIN7869924)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filamin A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Filamin A Antibody

Binding Specificity: AA 1025-1054

Purpose: Filamin A Antibody / FLNA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1025-1054 from the human protein was used as the immunogen for the Filamin A antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Filamin A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Filamin A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Alternative Name: Filamin A

Background: Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location