CBS antibody (AA 104-133)

Catalog No. ABIN7869937

The Rabbit Polyclonal anti-CBS antibody (ABIN7869937) specifically detects CBS in WB, IF, IHC (p) and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for CBS antibody (AA 104-133) (ABIN7869937)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-CBS Antibody

Binding Specificity: AA 104-133

Purpose: Cystathionine Beta Synthase Antibody / CBS

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 104-133 from the human protein was used as the immunogen for the Cystathionine Beta Synthase antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Cystathionine Beta Synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Cystathionine Beta Synthase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name: Cystathionine Beta Synthase

Background: CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

UniProt: P35520