FOXL1 antibody (AA 104-258)

Catalog No. ABIN7869967

The Mouse Monoclonal anti-FOXL1 antibody (Clone PCRP-FOXL1-1F8) (ABIN7869967) specifically detects FOXL1 in WB, IHC (p), IF and FACS. The antibody is reactive with Human samples.

Quick Overview for FOXL1 antibody (AA 104-258) (ABIN7869967)

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-FOXL1-1F8

Product Details anti-FOXL1 Antibody

Binding Specificity: AA 104-258

Purpose: FOXL1 Antibody

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 104-258 was used as the immunogen for the FOXL1 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the FOXL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FOXL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOXL1

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Alternative Name: FOXL1

Background: FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyers patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

UniProt: Q12951