Uroplakin 1B antibody (AA 107-216)

Catalog No. ABIN7870002

The Rabbit Polyclonal anti-Uroplakin 1B antibody is suitable to detect Uroplakin 1B in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Uroplakin 1B antibody (AA 107-216) (ABIN7870002)

Target: Uroplakin 1B (UPK1B)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Uroplakin 1B Antibody

Binding Specificity: AA 107-216

Purpose: UPK1B Antibody / Uroplakin 1B

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids I107-Q216) was used as the immunogen for the UPK1B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the UPK1B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the UPK1B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: UPK1B

Background: Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.

UniProt: O75841