FLI1 antibody (AA 107-261)

Catalog No. ABIN7870008

The Mouse Monoclonal anti-FLI1 antibody is suitable to detect FLI1 in samples from Human. It has been validated for ELISA.

Quick Overview for FLI1 antibody (AA 107-261) (ABIN7870008)

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FLI1 antibody is un-conjugated

Application: ELISA

Clone: FLI1-3183

Product Details anti-FLI1 Antibody

Binding Specificity: AA 107-261

Purpose: FLI1 Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 107-261 from the human protein was used as the immunogen for the FLI1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the FLI1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the FLI1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FLI1

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Alternative Name: FLI1

Background: Recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewings Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

UniProt: Q01543