TXNDC5 antibody (AA 109-403)

Catalog No. ABIN7870056

The Rabbit Polyclonal anti-TXNDC5 antibody is suitable to detect TXNDC5 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and FACS.

Quick Overview for TXNDC5 antibody (AA 109-403) (ABIN7870056)

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-TXNDC5 Antibody

Binding Specificity: AA 109-403

Purpose: TXNDC5 Antibody / Thioredoxin domain-containing protein 5

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M109-R403) was used as the immunogen for the TXNDC5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TXNDC5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TXNDC5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TXNDC5

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Alternative Name: TXNDC5

Background: Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.

UniProt: Q8NBS9

Pathways: Cell RedoxHomeostasis