Cadherin 20 antibody (AA 111-140)

Catalog No. ABIN7870114

The Rabbit Polyclonal anti-Cadherin 20 antibody (ABIN7870114) specifically detects Cadherin 20 in WB, FACS and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for Cadherin 20 antibody (AA 111-140) (ABIN7870114)

Target: Cadherin 20 (CDH20)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 20 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cadherin 20 Antibody

Binding Specificity: AA 111-140

Purpose: Cadherin 20 Antibody / CDH20

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 111-140 from the human protein was used as the immunogen for the Cadherin 20 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Cadherin 20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Cadherin 20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cadherin 20

Target: Cadherin 20 (CDH20)

Alternative Name: Cadherin 20

Background: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

UniProt: Q9HBT6