Neurocan antibody (AA 1140-1179)

Catalog No. ABIN7870196

This Rabbit Polyclonal antibody specifically detects Neurocan in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Neurocan antibody (AA 1140-1179) (ABIN7870196)

Target: Neurocan (NCAN)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurocan antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Neurocan Antibody

Binding Specificity: AA 1140-1179

Purpose: NCAN Antibody / Neurocan

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids H1140-A1179) was used as the immunogen for the NCAN antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NCAN antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NCAN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Neurocan

Target: Neurocan (NCAN)

Alternative Name: NCAN

Background: Neurocan core protein is a protein that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and migration. In the human subjects, it was found that NCAN genotype was strongly associated with manic symptoms but not with depressive symptoms. In the mice, the absence of functional Neurocan resulted in a variety of manic-like behaviors, which could be normalized by administering lithium.

UniProt: O14594

Pathways: Glycosaminoglycan Metabolic Process