PRODH antibody (AA 116-433)

Catalog No. ABIN7870237

The Rabbit Polyclonal anti-PRODH antibody (ABIN7870237) specifically detects PRODH in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PRODH antibody (AA 116-433) (ABIN7870237)

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRODH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-PRODH Antibody

Binding Specificity: AA 116-433

Purpose: Proline dehydrogenase 1 Antibody / PRODH

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (H116-E433) was used as the immunogen for the Proline dehydrogenase 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Proline dehydrogenase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Proline dehydrogenase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PRODH

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Alternative Name: Proline dehydrogenase 1

Background: Proline dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the PRODH gene. This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: O43272

Pathways: Response to Water Deprivation, Monocarboxylic Acid Catabolic Process