c-Rel antibody (AA 116-610)

Catalog No. ABIN7870241

This Rabbit Polyclonal antibody specifically detects c-Rel in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for c-Rel antibody (AA 116-610) (ABIN7870241)

Target: c-Rel (REL proto-oncogene (c-Rel))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-Rel antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-c-Rel Antibody

Binding Specificity: AA 116-610

Purpose: REL Antibody / c-Rel

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids K116-D610) was used as the immunogen for the REL antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the REL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the REL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Alternative Name: REL

Background: The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q04864