INPPL1 antibody (AA 1172-1258)

Catalog No. ABIN7870252

The Mouse Monoclonal anti-INPPL1 antibody (Clone 8C13) (ABIN7870252) specifically detects INPPL1 in WB, IHC (p), IF and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for INPPL1 antibody (AA 1172-1258) (ABIN7870252)

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This INPPL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 8C13

Product Details anti-INPPL1 Antibody

Binding Specificity: AA 1172-1258

Purpose: INPPL1 Antibody / SHIP2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R1172-K1258) was used as the immunogen for the INPPL1 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the INPPL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the INPPL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for INPPL1

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Alternative Name: INPPL1

Background: SH2-domain containing Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 is an enzyme that in humans is encoded by the INPPL1 gene. The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

UniProt: O15357

Pathways: Platelet-derived growth Factor Receptor Signaling