Angiomotin antibody (AA 12-622)

Catalog No. ABIN7870301

This Rabbit Polyclonal antibody specifically detects Angiomotin in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for Angiomotin antibody (AA 12-622) (ABIN7870301)

Target: Angiomotin (AMOT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiomotin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-Angiomotin Antibody

Binding Specificity: AA 12-622

Purpose: Angiomotin Antibody / AMOT

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids T12-Q622) was used as the immunogen for the Angiomotin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Angiomotin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Angiomotin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Angiomotin

Target: Angiomotin (AMOT)

Alternative Name: Angiomotin

Background: Angiomotin (AMOT) is a protein that in humans is encoded by the AMOT gene. This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size