SRI antibody (AA 121-161)

Catalog No. ABIN7870317

The Rabbit Polyclonal anti-SRI antibody is suitable to detect SRI in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for SRI antibody (AA 121-161) (ABIN7870317)

Target: SRI (Sorcin (SRI))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-SRI Antibody

Binding Specificity: AA 121-161

Purpose: Sorcin Antibody / SRI

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D121-A161) was used as the immunogen for the Sorcin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Sorcin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Sorcin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SRI

Target: SRI (Sorcin (SRI))

Alternative Name: Sorcin

Background: Sorcin is a protein that in humans is encoded by the SRI gene. It is mapped to 7q21.1. This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.

UniProt: P30626

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity