Glucuronidase beta antibody (AA 122-575)

Catalog No. ABIN7870340

This Rabbit Polyclonal antibody specifically detects Glucuronidase beta in WB, ELISA and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for Glucuronidase beta antibody (AA 122-575) (ABIN7870340)

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucuronidase beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glucuronidase beta Antibody

Binding Specificity: AA 122-575

Purpose: Gusb Antibody / Beta Glucuronidase

Purification: Affinity purified

Immunogen: A mouse recombinant protein (amino acids R122-E575) was used as the immunogen for the Gusb antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Gusb antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Gusb antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Glucuronidase beta

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Alternative Name: Gusb

Background: Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

UniProt: P12265

Pathways: Glycosaminoglycan Metabolic Process