RAB7L1
Reactivity: Human
WB
Host: Mouse
Monoclonal
L6G11
unconjugated
Application Notes
The stated application concentrations are suggested starting points. Titration of the RAB29 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store the RAB29 antibody at -20oC.
Target
RAB7L1
(RAB7, Member RAS Oncogene Family-Like 1 (RAB7L1))
Alternative Name
RAB29
Background
RAB7L1/RAB29 is involved in the movement of various molecules within cells, helping to maintain their proper function and organization. It is involvement in the endocytic pathway, where it helps to ensure that molecules are transported to the correct destination within the cell. This process is crucial for maintaining cellular homeostasis and responding to external signals. RAB29 also plays a critical role in autophagy, a process in which cells degrade and recycle damaged or unnecessary components. By regulating the trafficking of autophagosomes, the structures responsible for engulfing and degrading cellular material, RAB29 helps to maintain cell viability and prevent the accumulation of toxic substances. In addition to its roles in cellular trafficking and recycling, RAB29 has also been implicated in various disease processes, including cancer and neurodegenerative disorders.