IMPDH1 antibody (AA 123-500)

Catalog No. ABIN7870357

The Rabbit Polyclonal anti-IMPDH1 antibody (ABIN7870357) specifically detects IMPDH1 in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for IMPDH1 antibody (AA 123-500) (ABIN7870357)

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-IMPDH1 Antibody

Binding Specificity: AA 123-500

Purpose: IMPDH1 Antibody / IMP dehydrogenase 1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids P123-E500) was used as the immunogen for the IMPDH1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IMPDH1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IMPDH1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Alternative Name: IMPDH1

Background: Inosine-5'-monophosphate dehydrogenase 1, also known as IMP dehydrogenase 1, is an enzyme that in humans is encoded by the IMPDH1 gene. The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process