SKAP2 antibody (AA 124-208)

Catalog No. ABIN7870365

The Rabbit Polyclonal anti-SKAP2 antibody is suitable to detect SKAP2 in samples from Human and Mouse. It has been validated for WB, ELISA and FACS.

Quick Overview for SKAP2 antibody (AA 124-208) (ABIN7870365)

Target: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SKAP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SKAP2 Antibody

Binding Specificity: AA 124-208

Purpose: SKAP2 Antibody / PRAP / SCAP2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E124-E208) was used as the immunogen for the SKAP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SKAP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SKAP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SKAP2

Target: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Alternative Name: SKAP2

Background: Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: O75563