AMOTL2 antibody (AA 126-152)

Catalog No. ABIN7870388

This Rabbit Polyclonal antibody specifically detects AMOTL2 in WB. It exhibits reactivity toward Human.

Quick Overview for AMOTL2 antibody (AA 126-152) (ABIN7870388)

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMOTL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AMOTL2 Antibody

Binding Specificity: AA 126-152

Purpose: AMOTL2 Antibody / Angiomotin-like protein 2

Purification: Antigen affinity

Immunogen: A portion of amino acids 126-152 from the human protein was used as the immunogen for the AMOTL2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the AMOTL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the AMOTL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for AMOTL2

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Alternative Name: AMOTL2

Background: AMOTL2 is a member of the angiomotin family of proteins, which are involved in the development and maintenance of blood vessels. It functions as a scaffold protein that helps to organize signaling pathways involved in cell growth and movement. Studies have shown that AMOTL2 is essential for normal development and function of multiple tissues and organs, including the heart, lungs, and kidneys. One of the most intriguing aspects of AMOTL2 is its potential role in cancer progression. Research has shown that dysregulation of AMOTL2 expression is associated with various types of cancer, including breast, lung, and prostate cancer. In some cases, AMOTL2 acts as a tumor suppressor, inhibiting cancer cell growth and metastasis. In other cases, it can promote tumor progression by enhancing angiogenesis and invasiveness.

UniProt: Q9Y2J4