Ataxin 2 antibody (AA 1278-1313)

Catalog No. ABIN7870407

The Rabbit Polyclonal anti-Ataxin 2 antibody is suitable to detect Ataxin 2 in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for Ataxin 2 antibody (AA 1278-1313) (ABIN7870407)

Target: Ataxin 2 (ATXN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Ataxin 2 Antibody

Binding Specificity: AA 1278-1313

Purpose: SCA2 Antibody / ATXN2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q1278-L1313) was used as the immunogen for the SCA2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SCA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SCA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Ataxin 2

Target: Ataxin 2 (ATXN2)

Alternative Name: SCA2

Background: Ataxin-2, the protein encoded by the ATXN2 gene, contains a polyglutamine tract, long expansions (greater than 33 repeats) of which result in spinocerebellar ataxia-2 (SCA2), an autosomal dominant form of olivopontocerebellar atrophy. The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. Ataxin-2 associates with L- and T-plastin and that overexpression of ataxin-2 leads to accumulation of T-plastin in mammalian cells.

UniProt: Q99700

Pathways: Ribonucleoprotein Complex Subunit Organization